Avian influenza viruses could spawn the next human pandemic

March 13, 2023

The team created a database of more than 70,000 records of animal influenza from 1970 to 2016, providing insights into the trends of these viruses over time and space. It gives public health authorities a framework to detect and track viral outbreaks in animals that threaten to emerge in human populations. “This generates a solid foundation for understanding how, when and where animal influenza viruses could evolve into pandemic agents,” Professor Ward said. Birds are natural hosts of a huge range of avian influenza subtypes. This, say the authors, increases the likelihood that bird flu could become zoonotic, that is, transfer from animal to human.

Avian influenza H5N1 under an electron microscope [Credit: Cynthia Goldsmith, Jackie Katz]

Their study, published in One Health, is the result of a partnership project between Fudan University and the University of Sydney, led by Chinese researchers and co-authored by Professor Michael Ward from the Sydney School of Veterinary Science.

The team created a database of more than 70,000 records of animal influenza from 1970 to 2016, providing insights into the trends of these viruses over time and space. It gives public health authorities a framework to detect and track viral outbreaks in animals that threaten to emerge in human populations.

“This generates a solid foundation for understanding how, when and where animal influenza viruses could evolve into pandemic agents,” Professor Ward said.

“We are recovering from the coronavirus pandemic now, but a flu virus that flares up and takes hold in humans has the potential to dwarf the impact from COVID-19 given the high mortality rates caused by some animal viruses.”

The researchers concluded that bird flu might be the source of a new pandemic strain. Birds are natural hosts of a huge range of avian influenza subtypes. This, say the authors, increases the likelihood that bird flu could become zoonotic, that is, transfer from animal to human.

The source of this news is from University of Sydney

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